The goal of this clinical trial is to learn whether adding cilostazol to aspirin or clopidogrel prevents stroke and heart attack in people who have had a stroke or mini-stroke.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
2,000
Cilostazol 100 mg tablet taken orally twice daily following an initial 2-week period during which cilostazol is dosed at 100 mg tablet taken orally once daily to maximize tolerability.
Placebo 100 mg tablet twice taken orally daily following an initial 2-week period during which placebo is dosed at 100 mg taken orally once daily to maximize tolerability.
Stanford University
Stanford, California, United States
Major adverse cardiovascular event (MACE)
Time to stroke (ischemic and hemorrhagic), acute myocardial infarction, or vascular death
Time frame: Up to 4 years after randomization
Ischemic stroke
Time to ischemic stroke
Time frame: Up to 4 years after randomization
Major hemorrhage
Time to major hemorrhage
Time frame: Up to 4 years after randomization
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