This study aims to develop and validate a simple, accurate model to predict mortality after non-cardiac surgery.
This retrospective multi-center cohort study aimed to develop and externally validate a predictive model for postoperative mortality in adult patients undergoing non-cardiac surgery. The development cohort included patients from Asan Medical Center, and validation was performed using data from Seoul National University Hospital and Samsung Medical Center. Mortality was assessed at 30 days, 180 days, 1 year, and overall follow-up. The model was developed using LASSO logistic regression and evaluated for discrimination and calibration across cohorts.
Study Type
OBSERVATIONAL
Enrollment
642,377
Participants underwent non-cardiac surgery and were followed retrospectively without any experimental intervention. Data were collected from electronic medical records and national death registry to assess postoperative mortality outcomes.
Asan Medical Center, University of Ulsan College of Medicine
Seoul, South Korea
30-day postoperative mortality
Death from any cause occurring within 30 days after non-cardiac surgery, ascertained from hospital records and national death registry data.
Time frame: Up to 30 days after surgery
180-day postoperative mortality
Death from any cause within 180 days after non-cardiac surgery.
Time frame: Up to 180 days after surgery
1-year postoperative mortality
Death from any cause within 365 days after non-cardiac surgery.
Time frame: Up to 1 year after surgery
Overall postoperative mortality
Death from any cause during the entire follow-up period after non-cardiac surgery.
Time frame: Through study completion (median follow-up: approximately 5 years, maximum: 13 years)
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