Effect of Acute Endurance Exercise on the Production of FGF21 and Follistatin in Patients With Hepatocellular Carcinoma

Inclusion Criteria: * Hepatocellular carcinoma developed on cirrhosis * Cirrhosis of any etiology, defined by a liver elasticity measurement \>15kPa or a history of cirrhosis decompensation * Hepatocellular carcinoma with indication for treatment by immunotherapy or chemoembolization * Child-Pugh scores A and B7 * WHO score ≤ 2 * Affiliation to french national social security system Exclusion Criteria: * Hepatic encephalopathy grade II or higher * Bone metastasis * Surgery performed within 30 days prior to inclusion visit * Liver transplant * Muscle injury within 3 months of inclusion * Pregnant or breast-feeding women * Patients under legal protection (guardianship, curatorship, safeguard of justice) * Participation in another clinical trial within 10 days of inclusion