Efficacy of Olfactive Training on Loss of Smell and Taste Caused by SARS CoV2 COVID-19 (Covid-Smell)

N/ACompletedNCT07190911

Centre Hospitalier Universitaire de la Guadeloupe40 enrolled

Overview

The purpose of this study is to evaluate efficiency of two months of olfactive training on olfactory and taste loss secondary to covid-19. We will compare 2 groups : olfactive training group versus no olfactive training group.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

COVID - 19

Interventions

Olfactory rehabilitation consists of smelling a series of spices every day for 2 monthsOTHER

Olfactory rehabilitation consists of smelling a series of spices every day for 2 months: vanilla, coffee, dill, thyme, cinnamon, cloves, lavender, coriander, light vinegar, mint, and cumin. This rehabilitation is based on the protocols proposed by SFORL (French ORL society) and Oleszkiewicz et al.8 Allergies to certain spices will be noted at the start of the study: * in known allergy: change by another spice which belongs to the same chemical category. * in case of allergies to several scents: patient is not included in the study. * in case of allergy appearing during participation: clinical evaluation by ENT, change by another spice which belongs to the same chemical category. * in case of allergies to several scents occuring during participation: patient is excluded from the study.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * SARS-CoV-2 infection suspect or confirmed * supported by CHU Guadeloupe * with brutal olfactory or taste loss * affiliated or beneficiary of a social security scheme * informed consent signed Exclusion Criteria: * recent rhinosinusitis, less than 6 months * lingual pathology * communication disorder * Patients subject to a justice safeguard * Allergy to several spices that are part of the rehabilitation set * Pregnant or breastfeeding women * Absence of signed consent

Locations (1)

Chu de La Guadeloupe

Pointe-à-Pitre, Guadeloupe

Outcomes

Primary Outcomes

Taste and Smell Survey (TSS).

Patients will have this auto evaluation scale at the inclusion (D0) and 2 month after inclusion (D60).

Time frame: Baseline and 2 months

Secondary Outcomes

Sniffin' stick test :

The Sniffin' Stick Test assesses the sense of smell by measuring odor detection threshold, discrimination, and identification, and is used for diagnosing and monitoring olfactory disorders.

Time frame: 2 month

Olfaction and taste evolution evaluated with a daily visual scale

Visual analogue scale from 0 to 10 to assess dysosmia and dysgeusia, with 0 indicating normal function and 10 indicating complete deficit.

Time frame: Every day from inclusion to 2 months

Data from ClinicalTrials.gov

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