Psychological Distress in Malignant Tumor Patients: Effects on Treatment Adherence, Outcomes, and Quality of Life

N/ARecruitingNCT07193329

Gang Chen, MD2,000 enrolled

Overview

The goal of this observational study is to learn about the Psychological Distress in Malignant Tumor Patients about Effects on Treatment Adherence, Outcomes, and Quality of Life. The main question it aims to answer is: Does Psychological Distress affect Malignant Tumor Patients' Effects on Treatment Adherence, Outcomes, and Quality of Life? Malignant Tumor Patients with or without Psychological Distress will answer GAD-7 and PHQ-9 and their Treatment Adherence, Outcomes, and Quality of Life be recorded for 3 years.

Study Type

OBSERVATIONAL

Enrollment

2,000

Conditions

Psychological Distress Malignant Tumor

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * (1) Confirmed malignant tumors by imaging or pathology (such as hepatobiliary carcinoma, gastric cancer, breast cancer, lung cancer, etc.) * (2) Planning to receive or currently undergoing systemic treatment (such as surgery, chemotherapy, TACE, targeted therapy, etc.) * (3) Age ≥18 years old * (4) Sign the informed consent form and voluntarily participate in this study Exclusion Criteria: * (1) Combined with severe systemic diseases (such as severe cardiovascular and cerebrovascular diseases) * (2) There is severe cognitive impairment and it is impossible to complete the questionnaire assessment * (3) Incomplete clinical data or loss to follow-up

Locations (1)

Outcomes

Primary Outcomes

Objective Response Rate (ORR) by mRECIST (%)

Proportion of participants achieving complete response (CR) or partial response (PR) based on mRECIST criteria, measured on contrast-enhanced CT/MRI.

Time frame: at 4-12 weeks after treatment initiation.