Delirium Phenotypes and Subsequent Impairment During Transition From ICU to Hospital Wards

N/ARecruitingNCT07193797

Shanghai Zhongshan Hospital189 enrolled

Overview

The goal of this observational study is to learn about the disability profile during transition from ICU to hospital wards of delirium patients, including cognitive impairment, physical dysfunction and psychological disorders. The main question it aims to answer is: * What is the main rehabilitation problem during transition from ICU to hospital wards for patients who experienced ICU delirium? * Dose different phenotypes of ICU delirium shows different rehabilitation problem during ICU transition? Participants will be followed up and assessed by questionnaires after discharge from ICU to hospital wards until hospital discharge.

Study Type

OBSERVATIONAL

Enrollment

189

Conditions

Delirium Post ICU Syndrome

Interventions

Phenotypes of ICU deliriumOTHER

The included delirium patients will be divided into different phenotypes, according to delirium risk factors such as age, history of cerebrovascular accident, blood transfusion, surgery duration etc.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients aged above 18-year-old * at least one positive screening of CAM-ICU (Confusion Assessment Method for ICU) assessment during ICU stay * patients are transferred to hospital ward after ICU discharge Exclusion Criteria: * patients are with severe dementia * blindness, deafness or inability to understand mandarin * life expectancy of less than 24h * stayed in ICU more than one-month after the first CAM-ICU positive screening

Outcomes

Primary Outcomes

Physical impairment

The Modified Barthel Index is a widely used scale for assessing a patient's level of independence in activities of daily living (ADLs). Each activity is scored based on the degree of assistance required, with total scores typically ranging from 0 (complete dependence) to 100 (complete independence).

Time frame: At first, third day and fifth day after ICU discharge, at the 1 day of hospital discharge, one-month after hospital discharge

Cognitive impairment

The Mini-MoCA (Mini Montreal Cognitive Assessment) is a brief cognitive screening tool derived from the full MoCA, designed to rapidly assess cognitive function in clinical and hospital settings. It evaluates key domains such as orientation, attention, memory, language, and visuospatial skills, using a condensed format suitable for bedside.

Time frame: At first, third day and fifth day after ICU discharge, at the 1 day of hospital discharge, one-month after hospital discharge

Mental health

Hospital Anxiety and Depression Scale(HADS) is a 14-item tool used to screen for anxiety and depression in hospitalised patients. It includes two 7-item subscales, each scored 0-21, with higher scores indicate more severe psychological distress.

Time frame: At first, third day and fifth day after ICU discharge, at the 1 day of hospital discharge, one-month after hospital discharge

Secondary Outcomes

Hospital stay

Duration of hospital stay

Time frame: up to 30 days

In-hospital Mortality

Mortality during hospital stay

Time frame: up to 30 days

Delirium Phenotypes and Subsequent Impairment During Transition From ICU to Hospital Wards

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts