Comparison Of Keratometric Readings Pre and Post Pterygium Excision With Conjunctival Autograft Transplantation

N/AEnrolling By InvitationNCT07198126

Mughal Eye Trust Hospital130 enrolled

Overview

Pterygium, often called "surfer's eye," is a common eye condition in which a raised, fleshy growth of tissue extends from the white part of the eye onto the clear cornea. This growth can cause redness, irritation, blurred vision, and, in advanced cases, changes in the curvature of the cornea leading to distorted vision (astigmatism). The condition is more frequent in people exposed to sunlight, dust, and dry environments. The standard treatment for symptomatic pterygium is surgical removal. However, simple removal has a high chance of recurrence. To reduce this risk, surgeons commonly use a technique called conjunctival autograft transplantation, where a small piece of the patient's own conjunctiva is placed over the area after excision. This method not only lowers the recurrence rate but may also improve vision by reducing corneal irregularities. This study is designed to measure the changes in corneal curvature (keratometric readings) before and after pterygium excision with conjunctival autograft transplantation. By comparing preoperative and postoperative measurements, the study aims to determine how much this surgery improves corneal shape and reduces astigmatism. The hypothesis is that pterygium excision with conjunctival autograft transplantation will lead to a significant improvement in keratometric readings and reduce irregular astigmatism, thereby improving visual quality. This research will provide local evidence of the effectiveness of this procedure and help guide treatment strategies for patients suffering from pterygium-related visual problems.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

130

Conditions

Eligibility

Sex: ALLMin age: 30 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults of either sex aged \>30 to 70 years. * Phakic eyes. * Primary pterygium, Grade II or Grade III (as per protocol grading). * Presence of corneal astigmatism on pre-operative assessment. * Scheduled for pterygium excision with conjunctival autograft transplantation at the study site. * Able to provide written informed consent and to attend the 1-month postoperative assessment. Exclusion Criteria: * Pseudophakic or aphakic eyes. * Recurrent pterygium. * Prior keratoplasty or trabeculectomy in the study eye. * Keratoconus or other corneal pathologies that can independently induce astigmatism. * Lenticular astigmatism or significant lens pathology affecting refraction. * Eyes planned for simple pterygium excision without conjunctival autograft. * Any ocular condition or systemic illness judged likely to interfere with keratometric or refractive measurements, follow-up, or surgical safety.

Outcomes

Primary Outcomes

Change in Keratometric Readings (K1 and K2)

Keratometric readings, including the flat meridian (K1) and steep meridian (K2) of the anterior corneal surface, will be measured using a manual keratometer. The mean change in K-readings (measured in diopters) from baseline (pre-operative) to post-operative assessment will be calculated to evaluate corneal curvature improvement following pterygium excision with conjunctival autograft.

Time frame: Baseline (pre-operative) and 1 month post-operative.

Secondary Outcomes

Change in Astigmatism

Astigmatism will be measured using an automated refractometer. Both type (regular/irregular, with-the-rule/against-the-rule) and degree of astigmatism (in diopters) will be recorded. The reduction in astigmatism from baseline to post-operative follow-up will be assessed.