This study is a single-center, Phase IV clinical trial designed to collect and analyze data on the efficacy and safety of zanubrutinib as maintenance therapy following CAR-T cell therapy in subjects with non-Hodgkin B-cell lymphoma.
Study Type
OBSERVATIONAL
Enrollment
40
Patients achieving remission (complete or partial) at the 3-month post-CAR-T infusion assessment receive oral zanubrutinib capsules for maintenance therapy for 2 years.
Progression-free survival (PFS) rate at 24 months post-administration
Time frame: From date ofrandomization untilhe date of first documented progression , assessed up to 24 months
Progression-Free Survival (PFS)
Time frame: The time from the start of cell infusion to the first assessment of progression or death from any cause, assessed up to 5 years
Overall Survival (OS)
Time frame: From date of randomization untilhe date of first documented progression or date of death from any cause, whichever came first, assessed up to 5 years
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