Nu Skin (China) Daily-Use\&Health Products Co.,Ltd. has developed biophotonic scanners based on Raman spectroscopy, which measures skin carotenoid levels through hand skin scanning. In this study, the new Prysm device, which adopts new technology in a lower cost and more portable form, was used to measure skin carotenoid levels in a population, and the relationships between these levels and dietary habits and lifestyle factors were analyzed. The collected data included basic demographic information such as age, gender, smoking status, use of health products or nutritional supplements, and exercise habits, as well as physiological indicators such as BMI and body fat percentage. Subjective assessments were also obtained, including questionnaires on diet, skin condition, physical health, lifestyle, psychological status, and memory performance, alongside skin image analyses capturing parameters such as ITA°, L\*, a\*, b\*, glossiness, erythema, and pigmentation.
Study Type
OBSERVATIONAL
Enrollment
600
Shanghai China-norm Quality Technical Service Co., Ltd.
Shanghai, Shanghai Municipality, China
RECRUITINGSkin Carotenoid Index
The Prysm device utilizing hyperspectral absorption technology and the S3 device utilizing Raman spectroscopy technology, was used to measure the skin carotenoid index on subjects' fingers.
Time frame: At a single Day 1 visit after enrollment
Body Mass Index (BMI)
BMI is derived from the subjects' measured height and weight.
Time frame: At a single Day 1 visit after enrollment
Body Fat Percentage (BF%)
Time frame: At a single Day 1 visit after enrollment
Demographic Information
Including basic information such as gender, age, smoking status, use of health products or nutritional supplements, exercise habits.
Time frame: At a single Day 1 visit after enrollment
Dietary Intake
Subjects' dietary intake during the previous month was evaluated using Food Frequency Questionnaire - 25 (FFQ-25).
Time frame: At a single Day 1 visit after enrollment
Fitzpatrick Skin Type
Time frame: At a single Day 1 visit after enrollment
Skin Condition Self-Assessment
Subjects evaluated their skin condition during the previous month using a self-assessment questionnaire, covering dimensions such as photodamage, skin brightness, skin radiance, etc. Each dimension is scored from 0 to 9, with higher scores indicating better skin condition.
Time frame: At a single Day 1 visit after enrollment
The score of 36-Item Short Form Survey (SF-36)
It consists of 9 different dimensions: Physical Functioning (PF), Role-Physical (RP), Bodily Pain (BP), General Health (GH), Vitality (VT), Social Functioning (SF), Role-Emotional (RE), Mental Health (MH), Reported Health Transition (HT). Each dimension is scored from 0 to 100, higher scores reflect better health, functionality, and quality of life.
Time frame: At a single Day 1 visit after enrollment
Frequency of Physical Illness Symptoms
Subjects' immune function over the past year was evaluated using a questionnaire that collected the frequency of symptoms, including colds, influenza, allergies, etc. The total score ranges from 0 to 28, higher scores are associated with poorer immune function.
Time frame: At a single Day 1 visit after enrollment
Gastrointestinal Discomfort Symptoms
Subjects' gastrointestinal discomfort over the past month, including symptoms such as abdominal pain and bloating, was assessed using a questionnaire. The total score ranges from 20 to 100, and higher scores reflect more severe symptoms of gastrointestinal discomfort.
Time frame: At a single Day 1 visit after enrollment
Population-Based Visual Fatigue Scale Score
The questionnaire comprises 5 ocular symptoms (such as 'discomfort around the eyes', 'dryness of the eyes', etc.) and 6 visual and systemic symptoms (such as 'eye discomfort caused by screen brightness', 'anxiety associated with eye discomfort', etc.). The total score ranges from 0 to 44, higher scores reflect greater symptom severity.
Time frame: At a single Day 1 visit after enrollment
Traditional Chinese Medicine (TCM) Constitution Classification
Subjects' body constitution was evaluated and categorized based on the Traditional Chinese Medicine Constitution Classification and Determination Self-Assessment Form, following the standards of the China Association of Chinese Medicine. For each constitution classification, scores range from 0 to 100, and higher scores indicate greater alignment with specific body constitution.
Time frame: At a single Day 1 visit after enrollment
Brief Resilience Scale (BRS) Score
The BRS score is calculated by summing averaging the scores of all the six items, which ranges from 1 to 5. A higher average indicates greater psychological resilience, while a lower average indicates lower psychological resilience.
Time frame: At a single Day 1 visit after enrollment
Multifactorial Memory Questionnaire (MMQ) Score
It consists of three subscales: How I Feel About My Memory (scores range from 0 to 72), Memory Mistakes (scores range from 0 to 80) and Use of Memory Strategies (scores range from 0 to 68). A higher score indicates better memory.
Time frame: At a single Day 1 visit after enrollment
Facial image analysis
Including red area ratio, number and area ratio of color spots, L, a, b, and ITA °.
Time frame: At a single Day 1 visit after enrollment
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