Test Serum Clinical Study

Inclusion Criteria: 1. Chinese female with 25-40 years old. 2. All skin types by subjects' self-perceived. 3. Willing to perform HA injection. 4. Did not perform any of the beauty procedure projects in the past 6 months. 5. Lack of hydration, radiance, brightness, smoothness, firmness and elasticity by self-claimed. 6. Presenting with corresponding severity for the attribute evaluated by Dermatologist included: * Radiance, smoothness, elasticity, cheek plumpness and firmness: 3≤grade≤6. * Global fine lines: 3≤grade. * Underneath eye wrinkles: 2≤grade≤5. * Forehead wrinkles: 1\<grade≤4. * Glabella wrinkles: 1\<grade. 7. All accept not to use any cosmetics, skincare products, beauty equipment, all topical medications and cleansing products on face at visit days. 8. Did not participate any clinical test or cosmetic product test on skin within 1 months. 9. No disagreement of dermatologist because of other reasons that exclude the participation of the volunteer. 10. In general, good health at the time of the study. 11. Willing and able to participate as evidenced by signing of informed consent \& photo release form. 12. Must be willing to comply with all study protocol requirements. Exclusion Criteria: 1. Pregnant or breast-feeding woman or woman planning pregnancy during the study. 2. Subject deprived of rights by a court or administrative order. 3. Major subject to a guardianship order. 4. Subject residing in a health or social care establishment. 5. Patient in an emergency setting. 6. Subject with a skin disease in the test areas as well as skin allergy (particularly e.g., acne, rosacea, eczema). 7. Subject presenting a stable or progressive serious disease (per investigator's assessment). 8. Immuno-compromised subject. 9. Subject with history of allergy to cosmetic or personal care products or ingredients. 10. Subject presenting excessive exposure to sunlight or UV radiation (investigator's assessment). 11. Subject with history of sunlight sensitivity or allergies. 12. Subject regularly practicing aquatic or nautical sports. 13. Subject regularly attending a sauna. 14. Subject with physical highly sensitive constitution. 15. Subject with cardiovascular or circulatory history. 16. Subject with a history of skin cancer or malignant melanoma. 17. Intake of antihistamines, antibiotics, corticosteroids, non-steroidal anti-inflammatories or immune-suppressants in the last 6 months before study.