Pragmatic Analysis of Complex Radiotherapy Cases In Cancer of the Lung

N/AActive Not RecruitingNCT07202260

The Christie NHS Foundation Trust80 enrolled

Overview

This study focuses on improving care for people with lung cancer who face unusual or complex treatment situations.

By studying detailed patient data, researchers aim to find the best ways to treat these patients while reducing short- and long-term side effects. The findings will help refine radiotherapy treatments, ensuring they are as safe and effective as possible. Additionally, the results will provide doctors with better information to help patients understand the potential risks and benefits of their treatment options.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Lung Cancer (NSCLC)Lung Cancer (SCLC)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: Complex patients with lung cancer undergoing radiotherapy in one of the following groups; * Rare histology * Disease invading vascular structures * Co-existing interstitial lung disease (ILD) * Radical re-irradiation * Oligopersistent/oligoprogressive disease on immunotherapy or targeted therapies. Exclusion Criteria: * Include patients with stage IV disease who are receiving non-curative intent radiotherapy * There are no exclusion criteria relating to upper age limit or comorbidities.

Locations (1)

The Christie NHS Foundation Trust

Withington, Greater Manchester, United Kingdom

Outcomes

Primary Outcomes

Acute and late toxicity

\- Acute (\<90 days post radiotherapy) and late (\> 90 days post radiotherapy) toxicity according to common terminology criteria for adverse events (CTCAE) V5.

Time frame: 2 years

Data from ClinicalTrials.gov

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