Understanding the Public Impact on Dengue Vaccination Strategies in Yunnan Province, China: A Dynamic Transmission Modeling Study

N/AActive Not RecruitingNCT07206784

Fudan University220 enrolled

Overview

This study is a collaboration between the School of Public Health at Fudan University and the Xishuangbanna Center for Disease Control and Prevention in Yunnan Province, China. It aims to evaluate the public health impact of dengue vaccination strategies using dynamic transmission models. By simulating different vaccination scenarios, the study will assess the potential effectiveness and public health benefits of dengue vaccine introduction, providing scientific evidence to support local dengue prevention and control efforts.

Study Type

OBSERVATIONAL

Enrollment

220

Conditions

Dengue Vaccination Strategy Evaluation Transmission Modeling of Dengue Public Health Impact of Vaccination

Eligibility

Sex: ALLMin age: 3 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Resident of Jinghong City, Xishuangbanna Prefecture * Aged 3 years and above * Able and willing to provide informed consent (or have legal guardian consent for minors) * Available for blood sample collection between May and August 2025 Exclusion Criteria: * Individuals with bleeding disorders or other contraindications to blood draw * Individuals currently diagnosed with acute dengue infection

Outcomes

Primary Outcomes

Dengue Virus Serological Response (IgM and IgG Antibody Levels)

Time frame: From blood sample collection to the completion of laboratory analysis of dengue serology, serotype identification, and whole genome sequencing, from May to August 2025