The purpose of this research is to better understand how benign breast diseases might lead to breast cancer, focusing on genetic factors and including a diverse range of participants to improve future diagnosis and treatment.
Study Type
OBSERVATIONAL
Enrollment
4,500
Non-interventional study
Mayo Clinic in Florida
Jacksonville, Florida, United States
RECRUITINGMayo Clinic in Rochester
Rochester, Minnesota, United States
RECRUITINGPathologic features
Will examine pathologic features from benign tissue to define features related to breast cancer (BC) risk.
Time frame: Baseline (collection of blood or saliva sample)
Radiologic features
Will examine radiologic features from mammographic images at time of benign breast disease (BBD) to define features in mammogram images that predict BC risk among women who have a history of BBD. We will also assess whether these features predict BC risk among women without a history of BBD.
Time frame: Baseline (collection of blood or saliva sample)
Molecular features
Will examine molecular features to understand how molecular features, including DNA damage and repair work in the breast tissues of women with BBD and how this might relate to risk of developing BC
Time frame: Baseline (collection of blood or saliva sample)
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