The aim of this clinical study is to measure the levels of various trace elements in the blood serum of women with various gynecological diseases and to compare them with healthy controls. The main questions it aims to answer are: * Do trace element levels increase or decrease in endometriosis? * Do trace element levels increase or decrease in ovarian cancer patients? * Do trace element levels increase or decrease in endometrial cancer patients? Participants: Each member of the study group will visit the clinic only once and donate 5 ml of blood.
However, the serum trace elements profiles of individuals with endometriosis, ovarian cancer (OC), and endometrial cancer (EC) are not fully known. The purpose of this study is to examine the levels of trace element profiles in the blood serum of healthy people and individuals with gynecological disorders. The study group comprised of 40 women divided into four groups (n=10 each); endometriosis, endometrial cancer and ovarian cancer, and control group who were obstetrically and demographically similar. Inductively coupled plasma-mass spectrometry (ICP-MS) was used to assess serum trace element levels of lead, beryllium, vanadium, chromium, manganese, iron, cobalt, nickel, arsenic, selenium, molybdenum, cadmium, antimony, and phosphorus
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
40
5 mL of blood was collected from the right arms of all individuals in 4 different groups. Their serum was obtained.
sivas Cumhuriyet University
Sivas, Centre, Turkey (Türkiye)
Serum beryllium (Be) measurment
Measured beryllium (Be) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum phosphorus (P) measurment
Phosphorus levels (ppb) in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum vanadium (V) mesurment
Measured vanadium (V) levels (ppb) in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum chromium (Cr) measurment
Measured chromium (Cr) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum manganese (Mn) measurment
Measured manganese (Mn) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum iron (Fe) measurment
Measured iron (Fe) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum cobalt (Co) measurment
Measured cobalt (Co) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum nickel (Ni) measurment
Measured nickel (Ni) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum arsenic (As) measurment
Measured arsenic (As) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum selenium (Se) measurment
Measured selenium (Se) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum molybdenum (Mo) measurment
Measured molybdenum (Mo) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum cadmium (Cd) measurment
Measured cadmium (Cd) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum antimony (Sb) measurment
Measured antimony (Sb) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
Serum lead (Pb) measurment
Measured lead (Pb) levels in the serum samples of study group by ICP-MS baseline.
Time frame: 3 months
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