Based on the analysis of dietary characteristics, gut microbiota diversity, and composition, this study investigates the relationships between the dietary inflammatory potential, gut microbiota, and sarcopenia. Furthermore, it explores the mediating role of gut microbiota in the association between the dietary inflammatory index and the risk of sarcopenia. The findings are expected to provide insights into the mechanisms through which dietary inflammation influences the development and progression of sarcopenia, and to offer a basis for dietary and nutritional interventions aimed at preventing or managing this condition.
Study Type
OBSERVATIONAL
Enrollment
1,220
No Intervention
Lanzhou university
Lanzhou, Gansu, China
RECRUITINGThe prevalence of sarcopenia
The diagnosis of sarcopenia is confirmed according to the AWGS 2019 criteria, which requires the assessment of muscle strength, physical performance, and muscle mass.
Time frame: Through study completion, an average of 1 year
Change in absolute abundance of Faecalibacterium prausnitzii
16S rRNA absolute quantification was used to detect the microbial composition of the fecal samples.
Time frame: Through study completion, an average of 1 year
Dietary Characteristics
Dietary data were collected using a food frequency questionnaire (FFQ) to analyze dietary patterns and nutrient intake.
Time frame: Through study completion, an average of 1 year
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