The main objective of this trial is to investigate the effect of multiple oral doses of the strong CYP3A4 inhibitor itraconazole on the pharmacokinetics of a single dose of BI 3031185 following oral administration.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
14
BI 3031185
Itraconazole
Humanpharmakologisches Zentrum Biberach
Biberach, Germany
Area under the concentration-time curve of BI 3031185 in plasma over the time interval from 0 to the last quantifiable data point (AUC0-tz)
Time frame: Up to Day 13
Maximum measured concentration of BI 3031185 in plasma (Cmax)
Time frame: Up to Day 13
Area under the concentration-time curve of BI 3031185 in plasma over the time interval from 0 extrapolated to infinity (AUC0-∞)
Time frame: Up to Day 13
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