Axillary Nodal Burden in HER2+ and TNBC

Gangnam Severance Hospital1,571 enrolled

Overview

This study aimed to evaluated rates of pathologic axillary nodal metastasis in patients with with early-stage HER2-positive BC or TNBC who had clinically node-negative status on preoperative ultrasonography and underwent upfront breast-conserving surgery (BCS) with axillary surgery. In addition, this study aimed to identify subgroups in which SLNB omission may be feasible.

Study Type

OBSERVATIONAL

Enrollment

1,571

Conditions

Breast Cancer

Interventions

Breast conserving surgery with axillary surgeryPROCEDURE

In this study, all patients received breast conserving surgery with axillary surgery.

Eligibility

Sex: FEMALEMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: * HER2-positive breast cancer or TNBC * Patients who received upfront breast conserving surgery with axillary surgery * Patients who had a clinically axillary node negative disease Exclusion Criteria: * Patients who underwent mastectomy * Absence of axillary nodal assessment on ultrasonography * Patients who underwent mastectomy * Patients who underwent mastectomy

Locations (1)

Gangnam Severance Hospital, Yonsei University College of Medicine

Seoul, Please Select, South Korea

Outcomes

Primary Outcomes

Pathologic axillary lymph node metastasis rate

Time frame: Immediately after surgery

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.