Coronary CT Angiogram - Prognostic Value of Adverse Plaque Features in Guiding Treatment (CT-PLAQUE)

N/AActive Not RecruitingNCT07212751

The University of Hong Kong22,000 enrolled

Overview

The study aims at determining if the presence of adverse plaque features identified from the CT angiogram can help determine prognosis and guide treatment options.

Study Type

OBSERVATIONAL

Enrollment

22,000

Conditions

Determining if the Presence of Adverse Plaque Features Identified From the CT Angiogram Can Help Determining Prognosis and Guide Treatment Options

Interventions

CTCADIAGNOSTIC_TEST

Patient who is ≥ 18 years old presented with chest pain and has undergone CTA between 01-Jan-2012 and 31-Dec-2022 before treatment \- If multiple CTAs are taken, the most updated one before treatment commencement will be chosen.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient who is ≥ 18 years old presented with chest pain and has undergone CTA between 01-Jan-2012 and 31-Dec-2022 before treatment * If multiple CTAs are taken, the most updated one before treatment commencement will be chosen. Exclusion Criteria: * Patient who did not undergo cardiac CT scan due to inability to undergo cardiac CT scanning, kidney failure (serum creatinine \>250 μmol/L or estimated glomerular filtration rate \<30 mL/min), major allergy to contrast.

Locations (1)

The University of Hong Kong

Hong Kong, Hong Kong

Outcomes

Primary Outcomes

Nonfatal stroke, nonfatal myocardial infarction, and cardiovascular death and all-cause death

Time frame: 5 years after CTCA examinations

Secondary Outcomes

Total plaque, total calcified plaque, total non-calcified plaque, CT-FFR

Time frame: 5 years after CTCA examinations

Data from ClinicalTrials.gov

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