Ayahuasca and Esketamine for Major Depression

University of Sao Paulo22 enrolled

Overview

Double-blind, randomized trial comparing 4 weekly doses of oral ayahuasca and esketamine in patients with major depression.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Oral

oral

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Clinical diagnosis of depressive disorder Exclusion Criteria: \- Presence of psychiatric and other medical comorbidities

Hospital das Clínicas da FMRP-USP

Ribeirão Preto, São Paulo, Brazil

Beck Depression Inventory

21-question multiple-choice self-report inventory, where higher scores mean worse/more depressive symptoms

Time frame: 49 days

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