The objective of this trial is to assess the effect of BI 3000202 on the pharmacokinetics of rosuvastatin and digoxin given as a cocktail.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
14
Humanpharmakologisches Zentrum Biberach
Biberach, Germany
Area under the concentration-time curve of rosuvastatin in plasma over the time interval from 0 extrapolated to infinity (AUC0-∞)
Time frame: Up to Day 7
Area under the concentration-time curve of digoxin in plasma over the time interval from 0 extrapolated to infinity (AUC0-∞)
Time frame: Up to Day 7
Maximum measured concentration of rosuvastatin in plasma (Cmax)
Time frame: Up to Day 7
Maximum measured concentration of digoxin in plasma (Cmax)
Time frame: Up to Day 7
Area under the concentration-time curve of rosuvastatin in plasma over the time interval from 0 to the last quantifiable data point (AUC0-tz)
Time frame: Up to Day 7
Area under the concentration-time curve of digoxin in plasma over the time interval from 0 to the last quantifiable data point (AUC0-tz)
Time frame: Up to Day 7
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