This multicenter retrospective observational cohort study seeks to: 1. Classify surgical intent in patients with resected Intraductal Papillary Mucinous Neoplasms (IPMN) and quantify the proportion of IPMN-associated cancers diagnosed as overt pancreatic cancer with incidental IPMN association on pathology. 2. Compare clinicopathologic features and outcomes between surveillance-detected and incidentally detected IPMN-derived pancreatic cancers. 3. Revise and redefine risk features limited to patients undergoing surgery for IPMN-related indications, identifying optimal predictors of malignant IPMN (high-grade dysplasia or invasive cancer).
Study Type
OBSERVATIONAL
Enrollment
2,000
Mayo Clinic
Phoenix, Arizona, United States
RECRUITINGJohns Hopkins University
Baltimore, Maryland, United States
RECRUITINGMassachusetts General Hospital
Boston, Massachusetts, United States
RECRUITINGMayo Clinic
Rochester, Minnesota, United States
RECRUITINGNYU Langone Health
New York, New York, United States
RECRUITINGMemorial Sloan Kettering
New York, New York, United States
RECRUITINGDuke University
Durham, North Carolina, United States
RECRUITINGMD Anderson Cancer Center
Houston, Texas, United States
RECRUITINGNanjing University
Nanjing, China
RECRUITINGHeidelberg University
Heidelberg, Germany
RECRUITING...and 4 more locations
Grade of IPMN on Final Pathology
Time frame: Day 0 (Retrospective Analysis)
Recurrence Free Survival
Length of time from surgery for IPMN to recurrence.
Time frame: Day 0 (Retrospective Analysis)
Overall Survival
Length of time from surgery to death due to any cause.
Time frame: Day 0 (Retrospective Analysis)
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