Glycerol and sodium are osmotically-active ingredients that promote fluid retention via renal water reabsorption. The purpose of this study is to compare the effects of a glycerol-electrolyte beverage on fluid balance in healthy euhydrated men and women
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Enrollment
30
3 equal aliquots totaling 1 liter over a 30 min period, finishing each aliquot within 5 min followed.
3 equal aliquots totaling 1 liter over a 30 min period, finishing each aliquot within 5 min followed.
IMG Academy/GSSI Bradenton Gatorade Sports Science Institute
Bradenton, Florida, United States
RECRUITINGFluid balance
Calculated as change in nude body mass, %
Time frame: Through study completion, average of 3 weeks
Fluid Balance
Calculated as change in nude body mass, kg
Time frame: Through study completion, average of 3 weeks
Urine Mass
(g)
Time frame: Through study completion, average of 3 weeks
Beverage Hydration Index
calculated as the cumulative urine mass after drinking the placebo divided by the cumulative urine mass after drinking the test beverage
Time frame: Through study completion, average of 3 weeks
Urine specific gravity
(au)
Time frame: Through study completion, average of 3 weeks
Blood Pressure
systolic/diastolic (mmHg)
Time frame: Through study completion, average of 3 weeks
Heart Rate
bpm
Time frame: Through study completion, average of 3 weeks
Subjective measures of thirst, gastrointestinal discomfort, lightheadedness and headache
Rated on a 100-pt scale from none to extreme/severe for headache, lightheaded, stomach upset, nausea, abdominal discomfort, stomach fullness, thirsty, and hydrated.
Time frame: Through study completion, average of 3 weeks
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Menstrual categorization
Menstrual categorization chart (Elliott-Sale, 2023). Current status (e.g., contraception, regular periods or not, etc.).
Time frame: Reported by female subjects one time at screening visit.
Adverse Events
Documented changes in health and symptoms. Documented both in clinic and between visits in a provided paper log reviewed at each visit
Time frame: Through study completion, average of 3 weeks.