BSAFE is a randomized trial of a repeated-dose brief intervention to reduce overdose and risk behaviors among people who use stimulants who may have unintentional fentanyl use (UFU). It includes an established overdose education curriculum within an Informational-Motivation-Behavior (IMB) model. This study will test the efficacy of BSAFE vs attention-control.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
160
The intervention will include counseling sessions, reminder safety text messages, and linkage to care.
Attention control (videos)
San Francisco Department of Public Health
San Francisco, California, United States
Incidence of opioid overdose due to unintentional fentanyl use
Incidence of overdose will be measured by a composite measure of non-fatal and fatal overdose count collected by blinded assessors from Timeline Follow-Back (TLFB) every 4 months and vital record linkage for overdose fatalities.
Time frame: 16 months
Incidence of unintentional fentanyl use
Incidence of biomarker-confirmed unintentional fentanyl use, as determined by hair sampling for fentanyl and related analogues collected every 4 months.
Time frame: 16 months
Self-reported intentional opioid use
Self-report of fentanyl use and intentionality utilizing TimeLine Follow Back conducted at visits every 4 months.
Time frame: 16 months
Fentanyl positive urine
Proportion of fentanyl-positive urine drug screen results, as measured at study visits every 4 months.
Time frame: 16 months
Overdose resulting in Emergency Department presentation
Proportion of emergency room presentation for opioid overdose confirmed by electronic health record.
Time frame: 16 months
Use of overdose prevention strategies
Proportion of use of overdose prevention strategies, measured by self-report at each study visit every 4 months.
Time frame: 16 months
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