The objective of this protocol is to use a case-control paradigm to compare the response to an intravenous administration of kisspeptin in individuals with and without post-covid-19 syndrome. The study subjects will receive a single bolus of kisspeptin.
Delivery of Interventions: * Administration of a single kisspeptin bolus in a dosing range of 0.313 - 13.19 μg/kg * Blood sampling before and after administration of kisspeptin (two timepoints total)
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
40
Single bolus of kisspeptin
Massachusetts General Hospital
Boston, Massachusetts, United States
RECRUITINGDifference in mean luteinizing hormone (LH) amplitude between cases and controls
Difference between cases and controls of mean LH amplitude in response to kisspeptin
Time frame: Day of study visit (one to two hours)
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