A Clinical Investigation Into the Association of an Impaired Skin Barrier and Infant and Toddler Sensitive Skin

Inclusion Criteria: Subject pairs must meet all the following inclusion criteria for enrollment into the study (only one eligible child subject may be enrolled with any one parent subject). Parent subject and child subject: 1. Generally, in good health based on medical history reported by the parent subject. 2. Intends to complete the study and is willing and able to follow the subject responsibilities and undergo necessary testing procedures (tape stripping for baby subjects) and answer multiple questionnaires. Child subject: 3. Males and females aged 3 months-old up to 36 months-old (inclusive), targeting to complete with: Sensitive Skin Cohort (cohort 1): at least 30 child subjects in the 3 months-old up to 36 months-old range with 100% HCP diagnosed sensitive skin or parent-reported sensitive skin, and as defined as parent subjects who respond "Yes" to the Yes/No question "Do you believe your child has sensitive skin?" Non-Sensitive Skin Cohort (cohort 2): at least 30 child subjects in the 3 months-old up to 36 months-old age range with 100% having normal skin, has never been diagnosed with sensitive skin by a HCP, and as defined as parent subjects who respond "No" to the Yes/No question "Do you believe your child has sensitive skin?" 4. Has parent-reported natural skin tone "pale/fair to light white," "white to light beige," "beige to light tan/light olive," "medium tan/medium olive to light brown," "medium brown to dark brown," "darkest brown to darkest black", with every effort made to complete with at least 1 child subject for each skin tone per cohort. Parent subject: 5. Is at least 18 years old. 6. Is the primary caregiver and legal guardian of the child subject and is willing and able to present proof of legal guardianship (e.g. birth certificate/hospital discharge paperwork along with valid ID of legal guardian, etc.). 7. Is able to read, write, speak, and understand English. 8. Has signed the Consent for Photo Release and ICD including a Health Insurance Portability and Accountability Act (HIPAA) disclosure. 9. Intends to complete the study and is willing and able to follow all study instructions. 10. Parent subjects must agree to discontinue child's current face/body washes and face/body lotions for 24 hours prior to their study visit. Exclusion Criteria: Child Subject: 1. Is using Systemic or topical over-the-counter (OTC) or prescription medications that, in the Investigator's judgement, will affect skin condition or interfere with study evaluation. (Use of acetaminophen as needed is acceptable if it was instructed by the baby's pediatrician. Child vitamins are allowed.) 2. Is using topical steroids within 2 weeks before Visit 1. 3. Has Type 1 or Type 2 diabetes(reported by the parent) or is taking insulin or another anti-diabetic medication. 4. Is taking a medication that would mask an Adverse Event (AE) or confound the study results, including: 1. Immunosuppressive or steroidal drugs within 2 months before Visit 1 2. Non-steroidal anti-inflammatory drugs within 5 days before Visit 1 3. Antihistamines within 2 weeks before Visit 1 4. If an individual is taking one of these medication types, the individual is not considered eligible at screening. However, if a subject begins using one of these medications during the study, the Investigator should be consulted to consider the impact of the specific medication on subject safety and/or the study results. 5. Has a history of or a concurrent health/other condition/situation which may put the child subject at significant risk, confound the study results, or interfere significantly with the subject pair's participation in the study, as determined by the Investigator or designee. 6. Has a history of skin cancer. 7. Is simultaneously participating in another study involving product usage or skin sampling for the duration of the study or has participated in another study involving product usage or skin sampling within 14 days prior to Visit 1. 8. Has used new facial and body products and/or brands two weeks prior to Visit 1. 9. Is an immediate family member of the Investigator, Study Site, or Sponsor. 10. Presents with a skin condition that may confound the study results, increase risk to the subject, or influence the outcome of the study (e.g., psoriasis, eczema, atopic dermatitis, cutaneous xerosis, or active skin cancer), as determined by the Investigator or designee. Parent subject: 11. Is simultaneously participating in another study. 12. Is an employee/contractor of the Study Site or Sponsor or immediate family member of the PI, Study Site, or Sponsor.