This is a single-center, double-arm, patient masked, randomized controlled trial. Subjects will be enrolled in the Emergency Department at the Penn State Milton S. Hershey Medical Center. Eligible subjects must present to the ED and be diagnosed with a traumatic corneal abrasion. One eye from each patient will be considered the study eye.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
All qualified subjects will receive a drop of tetracaine. The treatment group will receive an Oasis 72-Hour collagen shield and instructions to take moxifloxacin 0.5% four times daily as well as ibuprofen 400 mg PO q4 hrs as needed for pain.
The control group will have a sham collagen shield placed (patient will have the impression a lens is placed but it will not actually remain on the eye), and will also be prescribed moxifloxacin 0.5% four times daily and ibuprofen 400 mg PO q4 hrs as needed for pain
Pain Score 4 hours
\- The primary endpoint will be pain score (10-point Liekert scale) 0=No pain 10=more pain
Time frame: four hours after leaving the emergency department.
Pain score 24 hours
The Secondary endpoint will be pain score (10-point Liekert scale) score 0=No pain 10=more pain
Time frame: 24 hours after discharge from the emergency department
Pain Score 72 hours
The Secondary endpoint will be pain score (10-point Liekert scale) score 0=No pain 10=more pain
Time frame: 72 hours after discharge from the emergency department
Dosage NSAID use in first 24 hours
Dosage of non-steroidal anti-inflammatory drugs (NSAIDs)
Time frame: in the first 24 hours after being discharged from the emergency department
Frequency NSAID 24 Hour
Time frame: 24 Hour
Pain score 24 hours
The Secondary endpoint will be pain score (10-point Liekert scale) score 0=No pain 10=more pain
Time frame: 24 hours after discharge from the emergency department
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