Comparison of Triglyceride-Glucose Index and Atherogenic Indices Between Patients With Lipedema and Obese Controls

Inclusion Criteria: * Clinically diagnosed with lipedema * Obese control group with BMI ≥30 kg/m² who do not meet lipedema criteria * Aged between 18 and 75 years * Availability of fasting lipid profile and fasting glucose tests within the past 3 months * Provided voluntary informed consent Exclusion Criteria: * Use of medications that routinely affect lipid or glucose metabolism: statins, fibrates, niacin, ezetimibe, high-dose omega-3 supplements, GLP-1 receptor agonists, SGLT2 inhibitors, or systemic corticosteroids (regular use within the past 3 months) * Presence of rheumatologic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) or active malignancy * Neurological disorders (e.g., polyneuropathy, multiple sclerosis, history of stroke) * Pregnancy or lactation * History of lower extremity surgery or major trauma within the past 6 months * Received injection therapy or physical therapy for the lower extremities within the past 6 months * Active infection or dermatological disease affecting the lower extremities * History of significant venous insufficiency or acute deep vein thrombosis (DVT) * Alcohol or substance abuse * Smoking