Use of Lactate-to-Albumin, CRP-to-Albumin, and Procalcitonin-to-Albumin Ratios to Predict Mortality in ICU Patients

N/ACompletedNCT07242027

Medical University of Silesia212 enrolled

Overview

This observational study aims to determine whether three blood test ratios - lactate-to-albumin, CRP-to-albumin, and procalcitonin-to-albumin - can predict in-hospital mortality among critically ill adults. The study includes all adult patients admitted in 2024 to the ICU Ward B at the Silesian Center for Heart Diseases (SCCS) in Zabrze. Researchers will analyze retrospective clinical and laboratory data from electronic medical records, including lab values collected at ICU admission, patient demographics, diagnoses, and outcomes. The biomarker ratios will be manually calculated in Excel and statistically evaluated. The main goal is to assess whether these ratios are associated with patient survival and to identify predictive cut-off values to support early risk stratification in the ICU setting.

Study Type

OBSERVATIONAL

Enrollment

212

Conditions

Sepsis Respiratory Failure Cardiac Arrest Circulatory Failure Critical Illness Sudden Cardiac Arrest

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years * Admission to ICU in 2024 * Availability of data for lactate, CRP, procalcitonin, and albumin Exclusion Criteria: * Missing outcome data (e.g. unknown survival status) * Lack of laboratory parameters necessary for ratio calculation

Outcomes

Primary Outcomes

In-hospital mortality

All-cause in-hospital mortality among ICU patients during the index hospitalization.

Time frame: 100 days from the date of ICU admission

Use of Lactate-to-Albumin, CRP-to-Albumin, and Procalcitonin-to-Albumin Ratios to Predict Mortality in ICU Patients

Overview

Conditions

Eligibility

Locations (1)

Outcomes

Primary Outcomes