IPP-PSP Block vs. SPSIPB in Breast Surgery

N/ANot Yet RecruitingNCT07246720

Zonguldak Bulent Ecevit University70 enrolled

Overview

This prospective, randomized clinical study aims to compare the analgesic efficacy of the interpectoral-pectoserratus plane block and the serratus posterior superior intercostal plane block for postoperative pain management in patients undergoing breast cancer surgery. Both techniques are ultrasound-guided regional anesthesia methods targeting different interfascial planes of the thoracic wall. The study will evaluate postoperative pain scores, opioid consumption, Quality of recovery and potential complications. The findings are expected to contribute to optimizing regional anesthesia strategies for enhanced recovery and improved analgesia following breast cancer surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Postoperative Acute Pain Breast Cancer Regional Anesthesia

Interventions

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 18-65 years of age * ASA I-II-III risk groups * Patients with informed consent * Patients undergoing breast cancer surgery Exclusion Criteria: • Ages \<18 and \>65 * ASA ≥ IV * History of allergy to local anesthetics * Known coagulation disorders * Infection near the insertion site * Chronic analgesic use * Patients with diabetes mellitus and those receiving neoadjuvant chemotherapy (due to potential impairment of pain sensation) * Body mass index \>30 * Dementia or confusion * Lack of cooperation

Outcomes

Primary Outcomes

Cumulative opioid consumption

Cumulative opioid consumption in the first 24 postoperative hours after the completion of the surgical procedure

Time frame: in the first 24 hours after completion of the surgical procedure

Secondary Outcomes

Postsurgical Quality of Recovery measured by the Quality of Recovery questionnaire

Postsurgical recovery by Quality of Recovery questionnaire (QoR-15) on first (D1) day after surgery. The minimum score on the Quality of Recovery questionnaire is 0 and the maximum score 150. Higher scores mean better quality of recovery.

Time frame: first day after surgery

Number of episodes of postoperative pain

Number of episodes of postoperative pain (NRS score ≥ 4) at rest and at deep inspiration in the first 24 postoperative hours after the completion of the surgical procedure

Time frame: In the first 24 hours after completion of the surgical procedure