The purpose of this study is to determine the pharmacokinetic and safety of BMS-986435 in participants with normal hepatic function and participants with different degrees of hepatic impairment
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
Specified dose on specified days
Maximum observed concentration (Cmax)
Time frame: Up to Day 45
Area under the concentration-time curve from time zero to time of last quantifiable concentration AUC(0-T)
Time frame: Up to Day 45
Area under the concentration-time curve from time zero extrapolated to infinite time AUC(INF)
Time frame: Up to Day 45
Number of participants with adverse events (AEs)
Time frame: Up to Day 45
Number of participants with serious adverse events (SAEs)
Time frame: Up to Day 45
Time of maximum observed concentration (Tmax)
Time frame: Up to Day 45
Half-life (T-HALF)
Time frame: Up to Day 45
Apparent total body clearance (CLT/F)
Time frame: Up to Day 45
Apparent volume of distribution at terminal phase (Vz/F)
Time frame: Up to Day 45
BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
CONTACT
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CONTACT
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