Study to examine the extent to which neurophysiological states recorded for a specific person on one day can be induced on a subsequent day
The study will be a single-arm design. It involves a longitudinal design in which subjective, physiological, and brain reactivity will be measured on 3 occasions, between \~2 weeks and \~4 months apart. The first assessment will be on a subjectively "good" day (mood rating above 7/10). The second will be on a subjectively "bad" day (mood rating below 3/10) and the third will be within a week of the second session. At the second and third sessions, participants will work to "restore" their brain state to that of the first assessment.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
60
Transcranial alternating current stimulation (tACS) is a widely used non-invasive brain stimulation method. The concept underlying alternating current is to simulate the naturally occurring rhythmic pattern of electrophysiological activity of the brain, which can be detected by electroencephalography (EEG). It involves the application of electrodes onto the scalp, which deliver sinusoidal alternating electric currents.
Participants will be shown their their brain EEG recordings and parameters from vocal recordings from their "backup" day, and asked to attempt to use behavioral strategies to match the recording
University of Pittsburgh
Pittsburgh, Pennsylvania, United States
RECRUITINGMean Change in electroencephalogram (EEG) Activity Across 4 Frequency Bands from Baseline
Change in the cosine of pre- and post- vectors for alpha, beta, theta, and gamma band activity from the first to third session
Time frame: 4 months
Mean Change in Happiness Visual Analogue Scale (VAS) Ratings From Baseline
Change in Happiness VAS rating (on a scale from 0-100) from the first to third session
Time frame: 4 months
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Participants will be given their subjective ratings and notes from a journaling interval to use as a target to restore their mood to how they were feeling on the Visit 1 backup day
Facial electrical stimulation, and chest-worn vibroacoustic stimulation will be used to affect facial muscle activity and peripheral physiology to better approximate previously assessed states.