Prediabetes is a major public health problem that increases the risk of developing type 2 diabetes mellitus and cardiovascular complications. Young adults represent an important age group in which early detection and intervention may prevent progression of the disease. The present study aims to identify factors associated with prediabetes and metabolic complications, and classify individuals based on clinical and biochemical profiles according to insulin resistance, dyslipidemia and fatty liver. This is an observational, cross-sectional study that will be conducted at Assiut University Hospital. Data will be collected through clinical examination, laboratory investigations, and assessment of metabolic profiles.
Study Type
OBSERVATIONAL
Enrollment
120
Participants will be classified into groups based on impaired fasting glucose, impaired post-prandial glucose, or impaired HbA1c according to ADA criteria
Correlation between prediabetes subtypes and metabolic syndrome
Primary Outcome Title: Correlation between prediabetes phenotypes and metabolic syndrome Outcome Measure: Prevalence (%) of metabolic syndrome within each prediabetes phenotype (IFG, IGT, combined IFG/IGT, elevated HbA1c). Description: Metabolic syndrome will be assessed at baseline according to the IDF definition. Participants will be classified into prediabetes phenotypes, and the proportion of individuals meeting metabolic syndrome criteria within each phenotype will be recorded. Time Frame: Baseline Unit of Measure: Percentage (%)
Time frame: At baseline (cross-sectional assessment during enrollment).
Factors affecting the correlation between prediabetes phenotypes and metabolic abnormalities (age, gender, family history, body physique, waist circumference and physical activity.
Secondary Outcome 1 Title: Age Description: Participant age in years. Unit of Measure: Years Time Frame: Baseline Secondary Outcome 2 Title: Sex Description: Participant sex as recorded at baseline. Unit of Measure: Categorical Time Frame: Baseline Secondary Outcome 3 Title: Family history of diabetes Description: Presence of family history of diabetes in first-degree relatives. Unit of Measure: Yes/No Time Frame: Baseline Secondary Outcome 4 Title: Weight Description: Body weight measured using a calibrated scale. Unit of Measure: Kilograms Time Frame: Baseline Secondary Outcome 5 Title: Height Description: Participant height measured using a stadiometer. Unit of Measure: Centimeters Time Frame: Baseline Secondary Outcome 6 Title: Body Mass Index (BMI) Description: BMI calculated as weight (kg) divided by height squared (m²). Unit of Measure: kg/m² Time Frame: Baseline Secondary Outcome 7 Title: Waist circumference Description: Waist circumference measured using a non-stretchab
Time frame: At baseline (cross-sectional assessment during enrollment)
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