Evaluate of the injectable platelet rich fibrin (I-PRF) with xenograft in Intrabony defects of Periodontitis patient stage III versus Xenograft alone.
All surgical procedures will be conducted by a single operator. Following administration of local anesthesia, intrasulcular incisions will beperformed buccally and lingually/palatally on the affected tooth and extended one adjacent tooth mesially and distally, using 15c blades. Following mucoperiosteal flap elevation, thorough debridement will be performed using ultrasonic scalers and curettes until defects are clear from any granulation tissue, and the defect morphology will be visually explored and recorded. In the group1: xenograft alone(Bovin xenograft)will be applied to the intrabony defect area. In the group 2: xenograft (Bovin xenograft) with injectable platelet Rich fibrin (I- PRF) will be applied to the intrabony defect area. Preperation of Injectable platelate Rich Fibrin (I-PRF) : will be prepared for each patient as follows: 5 ml of venous blood will be collected from the patient blood then placed in a plastic tube without any added material or coagulant and centrifuged at 700 rpm for 3 min. then mixed with Xenograft. Finally, the flap will be passively repositioned using interrupted 4-0 silk
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Elevation of papilla preservation flap at the site of 3mm infrabony defect ,prepearing the I-PRF which is obtained from the patients own blood , centrifuged at 700 rpm in 3 min and mixed with xenograft than placed at the defect area after removal all the granulation tissue follow up after 3 and 6 months intervals
Elevation of papilla preservation flap at the site of 3mm infrabony defect after removal all the granulation tissue, the xenograft alone inserted to the defect, suturing and follow up after 3 and 6 months intervals
Faculty of Dental Medicine for Girls, Al- Azhar University
Cairo, Cairo Governorate, Egypt
Ola Jamal
Cairo, Cairo Governorate, Egypt
Radiographic parameters
• The bone fill after 6 months postoperatively using digital periapical radiography using parallel technique.
Time frame: 6 months after treatment
Pocket depth (PD)
will be assessed by William graduated periodontal Probe in 4 surfaces of the tooth
Time frame: presurgically, 3 and 6 months interval after treatment
Plaque index (PI)
According to Silness \& Loe, 4 readings will be recorded for each surface of the teeth (buccal, lingual, mesial and distal) and it is given a score from 0-3
Time frame: pre-surgically 3 months and 6 months respectively
Gingival index (GI)
presence or absence of bleeding on upon gentle probing
Time frame: pre-surgically 3 months and 6 months respectively
Clinical attachment level (CAL)
will be measured from the cement-enamel junction to the base of the pocket
Time frame: pre-surgically 3 months and 6 months respectively
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