This prospective, randomized controlled trial aims to compare perioperative respiratory changes in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALRP) and open radical prostatectomy (ORP). The primary outcome is the change in peak expiratory flow (PEF) from the preoperative period to the early postoperative (2nd hour) period. Secondary outcomes include PEF recovery at 24 hours, and correlations between PEF change and intraoperative factors such as Trendelenburg angle, pneumoperitoneum duration, and ventilatory parameters.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
60
RALRP will be performed with pneumoperitoneum (12-15 mmHg CO₂ insufflation) and 25-30° Trendelenburg position. Peak Expiratory Flow (PEF) will be measured preoperatively, 2 hours postoperatively, and 24 hours postoperatively using the same handheld peak flow meter.
Ankara Bilkent City Hospital, Department of Anesthesiology
Ankara, Çankaya, Turkey (Türkiye)
Change in PEF (L/min)
Difference between preoperative and early postoperative PEF values.
Time frame: From preoperative baseline to postoperative 2nd hour
Change in PEF from preoperative to postoperative 24th hour
Evaluates recovery of PEF compared to baseline.
Time frame: From preoperative measurement (baseline) to postoperative 24th hour
Intraoperative parameters correlated with PEF reduction
Correlation between PEF change and intraoperative variables including Trendelenburg angle/duration, pneumoperitoneum pressure/duration, ventilatory pressures, and intraoperative fluid balance.
Time frame: From induction of anesthesia to end of surgery
Incidence of respiratory complications
Frequency of postoperative respiratory events such as desaturation, need for reintubation, or presence of chemosis.
Time frame: Within the first 24 hours after surgery
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