Comparative Study Between Intralesional Corticosteroid Injection Alone and Combined Intralesional Corticosteroid Injection With Either Long-pluse Nd YAG or Erbium Yag for Treating Hypertrophic or Keloid Scars

Somdech Phra Nangchao Sirikit Hospital20 enrolled

Overview

To compare the effectiveness of hypertrophic or keloid scar treatment with either intralesional corticosteroid injection alone or combined intralesional corticosteroid injection with either long-pulse ND YAG or Erbium YAG

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Hypertrophic Scar Keloid Laser

Interventions

Triamcinolone acetonide injectionDRUG

Long-pulse ND YAG and Erbium YAG laser device: Fotona Dynamis

Fotona dynamis: Long pulse Nd YAG + Er YAG laserDEVICE

Intralesional corticosteroid injection combine with long-pulse Neodynium-doped Yttrium Aluminium Garnet Laser (Nd-YAG) (IL KA + ND YAG)

Fotona Dynamis: Long pulse Nd YAG + Er YAG laserDEVICE

Intralesional corticosteroid injection combine with Erbium Yttrium Aluminium Garnet Laser (Er-YAG) (IL KA + Er YAG)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Individual with hypertrophic or keloid scars on any location * Size of hypertrophic or keloid scars not larger than 20 cms in diameter Exclusion Criteria: * Any topical or procedural treatment on scar in last 6 months * Current corticosteroid use * Bleeding disorders or coagulopathies * Pregnancy or nursing * Chronic kidney diseases * Chronic liver diseases

Locations (1)

Somdech Phra Nangchao Sirikit Hospital

Sattahip, Changwat Chon Buri, Thailand

Outcomes

Primary Outcomes

Vancouver scar scale

Vancouver scar scale to evaluate scar severity of keloid scar assessing 4 variations including vascularity, pigmentation, pliability, height scoring range from 0-13 (the more scores resembling the more severity)

Time frame: 5 months

Secondary Outcomes

Japan Scar Workshop Scar Scale

Japan Scar Workshop Scar Scale to evaluate scar severity of keloid scar assessing 2 main domains (risk factors and presenting symptoms) by 2 tables 1. Classification scoring range 0-5 = matured scars 6-15 = hypertrophic scars 16-25 = keloids 2. Evaluation for treatment \& follow ups scoring range from 0-18 (the more scores resembling the more severity)

Time frame: 5 months

Data from ClinicalTrials.gov

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