Effect of Adding Dexmedetomidine as Adjuvant toBupivacaine in Ultrasound Guided ExternalOblique Intercostal Plane Block in UpperAbdominal Cancer Surgery.
Effect of Adding Dexmedetomidine as Adjuvant toBupivacaine in Ultrasound Guided ExternalOblique Intercostal Plane Block in UpperAbdominal Cancer Surgery. A prospectiverandomized clinical trial
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
54
Dexmedetomidine as Adjuvant toBupivacaine in Ultrasound Guided ExternalOblique Intercostal Plane Block
Total Postoperative Opioid Consumption (mg of morphine equivalents)
To evaluate the effect of adding dexmedetomidine to bupivacaine on total opioid consumption within the first 24 hours after upper abdominal cancer surgery.
Time frame: 24 hours postoperative.
Postoperative Pain Intensity Using the Visual Analog Scale (VAS 0-10)
Pain scores will be assessed at rest and during movement using the Visual Analog Scale (0 = no pain, 10 = worst pain). Higher scores indicate worse pain.
Time frame: 2, 4, 6, 12, 18, and 24 hours postoperative.
Time to First Request for Rescue Analgesia.
Time from block performance until first request for analgesia.
Time frame: 24 hour postoperative
Number of Participants with Adverse Effects
Incidence of nausea, vomiting, hypotension, and bradycardia.
Time frame: first 2 hours postoperative.
patient satisfaction score
Patient satisfaction regarding pain control (0 = completely dissatisfied, 10 = fully satisfied). Higher scores indicate better satisfaction.
Time frame: 1 hour postoperative
Block-related complications.
Incidence of hematoma, infection, or local anesthetic systemic toxicity (LAST).
Time frame: intraoperative and 24 postoperative
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