Qualified subjects will be enrolled and randomized to either one of the two study groups described above based on their initial modified gingivitis and plaque scores. Subjects will be instructed to use the products according to the instructions provided. Subjects will return to the dental office for evaluation after two weeks, six weeks and three months of product use. All subjects will be followed for adverse events throughout the study
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
80
0.09% CPC, 0.28% zinc lactate and 500 ppm F as sodium fluoride
100 ppm F as sodium fluoride
Clinica Odontoiatrica Montesani
Roma, Rome, Italy
Modified Gingival Index
A Modified Gingivitis Index score from 0 to 4 will be assigned by the examiner to all tooth surfaces. In regards to the scale, lower number is a better outcome.
Time frame: baseline, 2 week, 6 week & 3 month
Saxton Bleeding Index
Gingival bleeding is assessed 30 seconds after probing; a score of 0 represents an absence of bleeding. a score of 1 is given if bleeding is observed within 30 seconds after probing and a score of 2 is given if bleeding is observed immediately on probing
Time frame: baseline, 2 week, 6 week & 3 month
Modified Quigley-Hein Plaque Index
Modified Quigley-Hein Plaque Index score of 0 to 5 will be assigned to all scoreable disclosed tooth surfaces. In regards to the scale, lower number is a better outcome.
Time frame: baseline, 2 week, 6 week & 3 month
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