Autogenous Tooth Bone Graft for Alveolar Socket Preservation

N/AActive Not RecruitingNCT07267637

Haifaa Mohammed Al-hussini20 enrolled

Overview

The purpose of this clinical experiment is to assess how well autogenous tooth bone grafting preserves the alveolar socket after surgical tooth extraction. Before being inserted into the socket, the graft is made from the patient's own extracted tooth and ground into a particle. Twenty Yemeni patients who needed their teeth extracted are included in the trial, and they will be followed up with clinical and radiographic procedures using cone-beam computed tomography (CBCT) for six months. The primary objective is to ascertain whether the autogenous dental bone graft can preserve the height, width, and density of alveolar bone, offering a secure, affordable, and biocompatible substitute for traditional grafting materials.

This interventional clinical study investigates the role of autogenous tooth bone graft in alveolar socket preservation after surgical tooth extraction. The extracted tooth is cleaned, dried, processed into particulate graft material manually using bone crusher, and disinfect and treated using (NaOH) and (Na CL). The graft particles are immediately placed into the fresh extraction socket and sutured. Twenty Yemeni patients requiring impacted lower third molar and upper canine teeth surgical extractions will be included. The healing process will be evaluated both clinically and radiographically over a 6-month period. Cone-beam computed tomography (CBCT) scans will be used to assess bone density and alveolar ridge dimensions before extraction and at six months' post-intervention. The study aims to determine whether autogenous tooth bone grafts can effectively reduce post-extraction alveolar bone resorption and maintain ridge dimensions, supporting their potential use as an autologous, biocompatible, and economically feasible graft material for clinical socket preservation.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Interventions

"Autogenous Tooth Bone Graft"BIOLOGICAL

"The intervention involves the use of the patient's own extracted tooth to create a bone graft for alveolar socket preservation following surgical tooth extraction. The patient's tooth is carefully processed to remove caries, periodontal ligaments, pulp, and any restorative materials, leaving behind a complete tooth structure (enamel, dentin, and cementum). This tooth is then crushed, disinfected, and treated before being placed into the empty socket. This graft helps maintain the structure of the alveolar bone by promoting natural bone regeneration and preventing resorption. The bone graft will be monitored for its efficacy in preserving alveolar bone height, width, and density, assessed using Cone Beam Computed Tomography (CBCT)."

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * \- Absence of systemic diseases. * Very good to accepted oral hygiene. * Patients with impacted teeth requiring extraction. * Patients between the ages of 16 and 50. * No history of smoking. * No history of any other drug use. * Patients who were cooperative, motivated, to attend the follow-up and maintenance visits. Exclusion Criteria: * Systemic conditions or pharmacological therapies that could be an absolute contraindication for the intervention (such as un controlled diabetics, immunocompromised states, or treatment with oral or parenteral bisphosphonates). * Poor oral hygiene. * Acute exacerbation of chronic infection like pain or swelling. * Pregnant women, children, elderly (\>60 years), physically and mentally challenged, terminally and seriously ill. * Hight Smoking tendency. * Patients who refused to participate in the trial. * Uncooperative Patients who won't be able to maintain the follow up visits

Outcomes

Primary Outcomes

"Alveolar Bone Height, Width, and Density Preservation with Autogenous Tooth Bone Graft"

This study aims to evaluate the effectiveness of autogenous tooth bone grafts in preserving alveolar bone following tooth extraction. The study will assess changes in alveolar bone height, width, and density using Cone Beam Computed Tomography (CBCT) at two time points: before extraction (baseline) and 6 months post-grafting. The outcome measures are: Alveolar Bone Height: Measured in millimeters using CBCT at baseline and 6 months. Alveolar Bone Width: Measured in millimeters using CBCT at baseline and 6 months. Alveolar Bone Density: Measured in Hounsfield units using CBCT at both time points. The intervention involves using the patient's own extracted tooth to create a bone graft placed into the socket, promoting healing and bone regeneration. This study will determine the effectiveness of autogenous tooth bone grafts in preventing bone resorption and preserving alveolar socket structure.

Time frame: "Before extraction and 6 months post-intervention"