This study investigates the effects of jackfruit oil extract on adipokine levels (Irisin, Omentin-1), brain-derived neurotrophic factor (BDNF), cognitive performance, and body measurements in healthy young boxers aged 18-25. Participants were randomly assigned to four groups receiving different doses of jackfruit oil extract (0, 100, 200, 300 mg/kg) or no supplement. Saliva samples, cognitive tests, and body measurements were collected at the start of the study and after 30 days to evaluate the outcomes.
This interventional study evaluates the effects of different doses of jackfruit oil extract on healthy young boxers aged 18-25. Participants were randomly assigned to four groups and followed for 30 days. Saliva samples were collected to measure irisin, omentin-1, and BDNF levels. Cognitive performance was assessed using the Wisconsin Card Sorting Test and the Trail Making Test. Anthropometric parameters including weight, BMI, waist, hip, chest, limb circumferences, and body composition were measured at baseline and on day 30. Statistical analyses were performed using SPSS version 26. ANOVA, Duncan, and Pearson correlation tests were used to determine significant differences and relationships between variables. This study is randomized and controlled. Participants receive either one of three doses of jackfruit oil extract or no supplement. The follow-up period is 30 days.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
30
Participants in the experimental group will receive a daily dose of jackfruit supplement during the study period. The supplement is administered orally and standardized for bioactive components. Participants in the control group will not receive any jackfruit supplement.
Bayburt Gençlik Merkezi Kapali Spor Salonu
Bayburt, Merkez, Turkey (Türkiye)
Salivary Irisin Level
Irisin levels measured from saliva samples collected from participants using the ELISA method.
Time frame: Day 0 and Day 30
Salivary Omentin-1 Level
Omentin-1 levels measured from saliva samples collected from participants using the ELISA method.
Time frame: Day 0 and Day 30.
Salivary BDNF Level
BDNF levels measured from saliva samples collected from participants using the ELISA method.
Time frame: Day 0 and Day 30.
Body Weight (kg)
Body weight measured using Tanita BC-418 bioimpedance device.
Time frame: Day 0 and Day 30
Height (cm)
Height measured using a standard stadiometer.
Time frame: Day 0 and Day 30
Body Mass Index (kg/m²)
BMI calculated using the formula weight (kg)/height (m²).
Time frame: Day 0 and Day 30
Waist Circumference (cm)
Waist circumference measured with a flexible tape measure.
Time frame: Day 0 and Day 30
Hip Circumference (cm)
Hip circumference measured with a flexible tape measure.
Time frame: Day 0 and Day 30
Chest Circumference (cm)
Chest circumference measured using a flexible tape measure.
Time frame: Day 0 and Day 30
Upper Arm Circumference (Right/Left, cm)
Right and left upper arm circumferences measured with a flexible tape measure.
Time frame: Day 0 and Day 30
Wrist Circumference (Right/Left, cm)
Right and left wrist circumferences measured with a flexible tape measure.
Time frame: Day 0 and Day 30
Thigh Circumference (Right/Left, cm)
Right and left thigh circumferences measured with a flexible tape measure.
Time frame: Day 0 and Day 30
Calf Circumference (Right/Left, cm)
Right and left calf circumferences measured with a flexible tape measure.
Time frame: Day 0 and Day 30
Total Body Fat Mass (kg)
Total body fat mass measured using Tanita BC-418.
Time frame: Day 0 and Day 30
Total Body Fat Percentage (%)
Total body fat percentage measured using Tanita BC-418.
Time frame: Day 0 and Day 30
Abdominal Fat Mass (kg)
Abdominal fat mass measured using Tanita BC-418.
Time frame: Day 0 and Day 30
Regional Fat Percentages (Right/Left Arm & Leg)
Regional fat percentages for arms and legs measured by Tanita BC-418.
Time frame: Day 0 and Day 30
Total Muscle Mass (kg)
Total muscle mass assessed using Tanita BC-418.
Time frame: Day 0 and Day 30
Regional Muscle Mass (Right/Left Arm & Leg, kg)
Regional muscle mass of arms and legs measured by Tanita BC-418.
Time frame: Day 0 and Day 30
Basal Metabolic Rate (BMR)
Basal metabolic rate calculated by Tanita BC-418.
Time frame: Day 0 and Day 30
Metabolic Age
Metabolic age estimated using Tanita BC-418 device.
Time frame: Day 0 and Day 30
Total Body Water (kg)
Total body water measured via bioimpedance analysis.
Time frame: Day 0 and Day 30
Total Body Water Percentage (%)
Total Body Water Percentage (%)
Time frame: Day 0 and Day 30
WCST Total Correct Responses
Total correct responses obtained from the Wisconsin Card Sorting Test.
Time frame: Day 0 and Day 30
WCST Total Incorrect Responses
Total incorrect responses measured using the Wisconsin Card Sorting Test.
Time frame: Day 0 and Day 30
WCST Perseverative Error Count
Perseverative errors recorded during the Wisconsin Card Sorting Test.
Time frame: Day 0 and Day 30
WCST Total Time (seconds)
Total time required to complete the Wisconsin Card Sorting Test.
Time frame: Day 0 and Day 30
Trail Making Test A Completion Time (seconds)
Completion time for Trail Making Test Part A.
Time frame: Day 0 and Day 30
Trail Making Test B Completion Time (seconds)
Completion time for Trail Making Test Part B.
Time frame: Day 0 and Day 30
Biomarker Correlations (Irisin-Omentin-BDNF vs. Dose/Day)
Pearson correlation analysis examining relationships between biomarkers and intervention dose/day.
Time frame: Based on Day 30 measurements
Safety Outcomes (Adverse Event Monitoring)
Monitoring of potential adverse events related to 300 mg/kg JOE administration.
Time frame: Continuous monitoring throughout 30 days
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