Comparison of the Pain Levels of Single-Dose Premedication With Piroxicam and Prednisolone on Post-Endodontic Pain in Single-Visit Root Canal Treatment of Premolars

Inclusion Criteria: * Healthy patient ranging between 18-40 years * Having at least one premolar with diagnosis of symptomatic irreversible pulpitis according to history, examination and radiographs. * Teeth having mature apex confirmed by periapical radiographs. Exclusion Criteria: * History of systemic disorders including HIV, Hepatitis * Pregnancy (As per Medical record/ Verbally) * Patient using medication such as analgesics or anti-inflammatory drugs * Patient allergic to lignocaine, piroxicam and prednisolone * Tooth not suitable for restoration * Periodontal probing depth ≥ 4mm * Retreatment cases * Patients having calcified canals assessed by radiographic findings