Bismuth-containing quadruple therapy was recommended as a first-line treatment for Helicobacter pylori infection. This study aimed to compare real-world outcomes of various potassium-competitive acid blockers (P-CABs) -based bismuth quadruple regimens and identify factors influencing treatment failure. A multicenter cohort study was conducted and study outcomes included eradication rates and incidence of adverse events.
Study Type
OBSERVATIONAL
Enrollment
1,730
Doctors prescribe Helicobacter pylori treatment regimens for patients based on current guidelines and consensus statements, tailored to individual circumstances,not involve any intervention procedures.
Qilu Hospital of Shandong University
Jinan, China
RECRUITINGEradication rate
Comparison of eradication rates among quadruple therapies for Helicobacter pylori
Time frame: 6-8 weeks after treatment completion
Adverse events
Time frame: lmmediately after treatment completion
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