Surgical Evacuation Versus Methotrexate Injection in Treatment of Caesarean Scar Pregnancy [Clinical Trial ]

Phase 2Not Yet RecruitingNCT07288307

Minia University42 enrolled

Overview

The aim of the study is to compare the effectiveness and the complications of Ultrasound guided surgical evacuation versus using combined local and systemic methotrexate injection for management of caesarean scar pregnancy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Caesarean Scar Pregnancy

Interventions

Surgical evacuation and methotrexate injectionPROCEDURE

Surgical evacuation of the scar pregnancy using ultrasound and local and systemic methotrexate injection

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: Gestation age Less than 12 weeks. Hemodynamically stable patient with un ruptured CSP. Non disturbed scar pregnancy . Acceptance of possible prolonged follow up, repeated HCG tests, the need for additional treatment doses and possible bleeding and subsequent hysterectomy. \- Exclusion Criteria: * Patient refuse TOP. Gestation age More than 12 weeks . Hemodynamically unstable patient with ruptured CSP. Contraindication for methotrexate as hepatic disorders, renal disorders ,hypersensitivity to the drug and autoimmune diseases.

Outcomes

Primary Outcomes

Success rate of treatment either by surgical evacuation or by methotrexate injection

The proportion of participants achieving complete resolution of caesarean scar pregnancy without the need of additional intervention