Patient with transfusion depandant beta thalassemia with accumulation of iron in their body affect pituitary gland and gonades lead to impaired their functions .
detection of any abnormalities in pituitary gland hormones ( FSH , LH , serum prolactin ) gonadal hormones ( serum testesterone , antimullerian hormone , INSL3 , inhibin B hormone )
Study Type
OBSERVATIONAL
Enrollment
80
transfusion depandant beta thalassemia with measure gonadal function serum INSL3 serum inhibin B serum AMH
gonadal function in transfusion depandant beta thalassemia
gonadal function assessment by Inhibin B hormone, INSL3 , serum testesterone that analysed in patient with age 10 - 18 year old for early detection of any abnormality
Time frame: through study completion, an average of 1 year
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