Women with psoriasis usually develop many complications including polysyctic ovarian syndrome (PCOS). Nowdays, diet restriction combimed with phsyical exercises may improve both problems
Forty Women with psoriasis with PCOS will be enrolled to be catogrized to Group I or group II. Group I will enroll twenty females with PCOS and Psoriasis who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks. Group II will will enroll twenty females with PCOS and Psoriasis who will follow low calorie diet and daily metformin for 12 weeks
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
Group I will enroll twenty females with PCOS and Psoriasis who will apply forty minutes walking on treadmill three times per week for 12 weeks. Also Group I will follow low calorie diet and daily metformin for 12 weeks.
Group II will will enroll twenty females with PCOS and Psoriasis who will follow low calorie diet and daily metformin for 12 weeks
Cairo University
Giza, Dokki, Egypt
RECRUITINGPsoariasis area and severity index
is an index used to express the severity of psoriasis. It combines the severity (erythema, induration and desquamation) and percentage of affected area
Time frame: it will be measured after 12 weeks
body mass index
it will be assessed after emptying bladder and bowel
Time frame: It will be measured after 12 weeks
waist circumference
it will be measured at level of ambilicus
Time frame: It will be measured after 12 weeks
waist hip ratio
it will be assessed after dividing waist circumference on hip circumference
Time frame: It will be measured after 12 weeks
testesterone
it will be assessed in serum
Time frame: it will be measured after 12 weeks
ratio of luteinizing hormone and follicle-stimulating hormone
it is anindicator on function of sex hormones
Time frame: It will be measured after 12 weeks
Dehydroepiandrosterone
it will be assessed in plasma
Time frame: It will be measured after 12 weeks
Dermatology life Quality Index
it assess impact of skin disease on quality of life
Time frame: It will be measured after 12 weeks
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insuiln
it will be assessed in plasma
Time frame: It will be measured after 12 weeks
fasting blood glucose
it will be assessed in plasma
Time frame: It will be measured after 12 weeks
HOMA-IR
Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) is classically considered to be a good insulin resistance (IR) index
Time frame: It will be measured after 12 weeks
triglycerides
it will be assessed in plasma
Time frame: It will be measured after 12 weeks
total cholesterol
it will be assessed in plasma
Time frame: It will be measured after 12 weeks
high density lipoprotein
it will be assessed in plasma
Time frame: It will be measured after 12 weeks
low density lipoprotein
it will be assessed in plasma
Time frame: It will be measured after 12 weeks
systolic blood pressure
it will be assessed via manual sphygmmanometer
Time frame: It will be measured after 12 weeks
diatolic blood pressure
it will be assessed via manual sphygmmanometer
Time frame: It will be measured after 12 weeks