To investigate the safety, efficacy, pharmacokinetics, and pharmacodynamics of SHR-2173 injection in patients with primary membranous nephropathy
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
75
SHR-2173 injection, with a total of 8 administrations
SHR-2173 injection, with a total of 16 administrations
SHR-2173 injection , with a total of 32 administrations
General hospital of eastern theater command
Nanjing, Jiangsu, China
RECRUITINGAdverse events
Time frame: Week0, 2, 4, 8, 12,16, 20, 24, 28, 32, 36, 40, 48 52
12-lead ECG
Time frame: Week4, 8, 12, 24, 28, 36, 52
The proportion of subjects who achieved overall response (including complete response (CR) and partial response (PR)).
Time frame: Week 12, 24, 36, 52
The proportion of subjects who achieved CR
Time frame: Week 12, 24, 36, 52
The proportion of subjects who achieved PR
Time frame: Week 12, 24, 36, 52
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