Serum Hyperbilirubinemia as an Early Predictive Factor for Complicated Appendicitis: Single Center Experience

Minia University400 enrolled

Overview

Serum total bilirubin provides a practical guide to early assessment of suspected appendicitis, supporting faster and more proportionate decisions-earlier escalation when overall risk is high and safe observation when it is low. Because testing is rapid, inexpensive, and universally available, integration into local diagnostic pathways is feasible.

Study Type

OBSERVATIONAL

Enrollment

400

Conditions

Appendicitis, Surgery

Interventions

AppendectomyPROCEDURE

Total bilirubin levels was measured preoperatively as part of the routine laboratory workup. Appendectomy done for all patients followed by histopathological evaluation of the excised appendix.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * All patients presented with right iliac fossa pain diagnosed clinically as acute appendicitis and had undergone appendectomy Exclusion Criteria: * patients with past history of jaundice * patients with history of hyperbilirubinemia hemolytic disease * positive hepatitis viruses * cholelithiasis * acquired or congenital biliary disease * cancer of the hepatobiliary system

Locations (1)

Minia university

Minya, Egypt

Outcomes

Primary Outcomes

measurement of serum total bilirubin in each case of appendicitis to clarify the relationship between serum hyperbilirubinemia and complicated appendicitis

Time frame: between September 2024 and August 2025

Data from ClinicalTrials.gov

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