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Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease

N/AActive Not RecruitingNCT07292311
University of Extremadura50 enrolled

Overview

This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD). Additionally, the study will assess the feasibility and potential benefits of an online therapeutic exercise program supervised by physiotherapists.

Patients with chronic kidney disease experience progressive muscle weakness and reduced physical capacity due to systemic inflammation, metabolic acidosis, and inactivity. This two-phase observational and interventional study, conducted in collaboration with the ALCER Association (Badajoz and Cáceres, Spain), will: 1. Determine the test-retest reliability of muscle assessment tools (isokinetic dynamometer, surface electromyography, and handheld dynamometry). 2. Implement and evaluate an online therapeutic exercise program supervised by physiotherapists. The project aims to provide valid and reliable protocols for neuromuscular assessment in CKD patients and explore the feasibility of remote therapeutic exercise.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

50

Conditions

Chronic Kidney DiseaseRenal Insufficiency, ChronicMuscle WeaknessSarcopeniaPhysical FitnessPhysical Therapy Modalities

Interventions

Reliability AssessmentDEVICE

Device: Isokinetic dynamometer and mDurance® surface EMG Test-retest reliability of isokinetic and surface EMG measurements in upper limb, trunk, and lower limb

Online Therapeutic ExerciseBEHAVIORAL

Behavioral: Online therapeutic exercise program 8-10 week supervised online program including resistance and mobility exercises

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:
Medical Language ↔ Plain English
Inclusion Criteria: * ≥18 years old. * Diagnosis of chronic kidney disease (hemodialysis, peritoneal dialysis, or kidney transplant). * Member of ALCER Association (Badajoz or Cáceres). * Medical clearance for physical testing/exercise. Exclusion Criteria: * Severe cognitive or communication impairment. * Unstable cardiovascular or musculoskeletal conditions. * Refusal to provide informed consent.

Locations (1)

Facultad de Enfermería y Terapia Ocupacional

Cáceres, Cáceres, Spain

Outcomes

Primary Outcomes

Test-retest reliability of surface EMG (Electromiography) activation.

RMS (root mean square). microvolts

Time frame: 7-10 days

Test-retest reliability of isokinetic strength

Intraclass Correlation Coefficient - ICC. Strength (kilograms)

Time frame: 7-10 days

Change in handgrip and limb strength measured by VALD dynamometry

strength (kilograms)

Time frame: Baseline and 12 weeks

Data from ClinicalTrials.gov

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