Boric Acid Versus 10% Povidone Iodine Solution in Treatment of Otomycosis

Mansoura University60 enrolled

Overview

This study compares two topical agents for the treatment of fungal infection of the external auditory canal: boric acid and a 10% povidone-iodine solution

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Otomycosis

Interventions

Boric acidDRUG

Boric acid is topically applied to the external auditory canal for treatment of otomycosis

Povidone iodine 10%DRUG

10% povidone iodine solution is topically applied to the external auditory canal for the treatment of otomycosis

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * all consecutive patients with otomycosis, recruited from the outpatient clinic during the study duration Exclusion Criteria: * tympanic membrane perforation * previous ear surgery * significant medical co-morbidities such as poorly controlled diabetes or immunocompromised patients * patient refusal to participate in the study

Locations (1)

Faculty of Medicine, Mansoura University

Al Mansurah, Dakahlia Governorate, Egypt

Outcomes

Primary Outcomes

objective clinical response

clinical response is assessed by ear examination by presence or absence of fungal hyphae inside the external auditory canal

Time frame: Days 7, 14, and 28 after treatment

Microbiological response

Microbiological response is evaluated by obtaining cultures from the external auditory canal searching for fungal growth

Time frame: day 28 after treatment

Secondary Outcomes

subjective pain response

pain is evaluated on a visual analogue scale from 0 to 10

Time frame: days 7, 14, and 28 after treatment

subjective itching response

itching is evaluated on a visual analogue scale from 0 to 10

Time frame: days 7, 14, and 28 after treatment

Data from ClinicalTrials.gov

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