The goal of this observational study is to assess the impact of endoscopic vacuum therapy in patients who underwent total gastrectomy due to gastric cancer and developed esophago-jejunal anastomotic leakage. The main outcomes to be investigated are the following: Primary endpoint: mortality rate Secondary endpoints: morbidity rate, time from AL diagnosis to discharge, patients satisfactory rate.
Patients who are diagnosed with asophago-jejunal anastomotic leakage will undergo endoscopic vacuum therapy. Local source control may be additionally achieved with para-anastomotic drains.
Study Type
OBSERVATIONAL
Enrollment
100
National Cancer Institute
Kyiv, Ukraine
RECRUITINGMortality rate
Mortality rate associated with endoscopic vacuum therapy
Time frame: 90 days after last endo-vac placement
Morbidity rate
Rate of complications associated with endoscopic vacuum therapy or ineffective local control
Time frame: 90 days after last endoscopic vacuum placement
Time from AL diagnosis to discharge
time from AL diagnosis to discharge
Time frame: The number of days from from AL diagnosis to discharge
Patients satisfactory rate
Patients satisfactory rate assessed by quality of life questionnaires and patient-reported outcomes scales
Time frame: 90 days after discharge, 365 days after discharge, 2/3/4/5 years after discharge
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