Accelerating Recovery After ICU Admission: Post-discharge Supplementation With Pasteurized Akkermansia Muciniphila.

Inclusion Criteria: * Age ≥18 years * Treated in the ICU for at least 2 days and discharged to a regular clinical ward * Diagnosed with sepsis during ICU admission * Received selective digestive decontamination (SDD) or cephalosporin * Capable of giving written informed consent Exclusion Criteria: * Recent major gastrointestinal surgery * Diagnosed with ulcerative colitis or Crohn's disease * Presence of a hematological malignancy and/or current use of immunomodulatory therapy (e.g., CAR-T cell therapy or immune checkpoint inhibitors) Use of systemic immunomodulatory drugs or corticosteroids (defined as ≥10 mg prednisone equivalent daily at ICU discharge), at the time of inclusion. * History of solid organ or stem cell transplantation * Pregnancy or lactation * Donation of blood or plasma within 30 days prior to inclusion or planned donation during the intervention period * Any other condition that, in the opinion of the investigator, could pose a risk to the subject or interfere with study result